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目的:评价无创正压通气(NIPPV)在抢救急性呼吸衰竭患者中的疗效。方法:对入选的38例急性呼吸衰竭患者使用无创正压呼吸机辅助通气,动态观察治疗前和治疗后2h动脉血气及生命体征变化。结果:38例患者中23例经NIPPV治疗2h后,PaO2明显升高(P<0.01),PaCO2明显降低(P<0.01),pH升高(P<0.05),有效率达63.2%(23/38)。对病因为AECOPD、间质性肺炎、急性左心衰及肺部感染的患者,疗效显著;而对病因为支气管哮喘、肺癌、ARDS及MOF患者疗效差。其中Ⅰ型呼衰成功率40.0%(6/15),Ⅱ型呼衰成功率78.5%(18/23),NIPPV对Ⅱ型呼衰救治成功率明显高于Ⅰ型呼衰(P<0.01)。结论:NIPPV在急性呼吸衰竭急救中疗效确切,应用时应掌握指征以提高疗效。
Objective: To evaluate the efficacy of noninvasive positive pressure ventilation (NIPPV) in the rescue of patients with acute respiratory failure. Methods: 38 patients with acute respiratory failure were selected non-invasive positive pressure ventilator-assisted ventilation, dynamic observation of arterial blood gas and vital signs before and after treatment 2h. Results: The PaO2 was significantly increased (P <0.01), the PaCO2 was significantly decreased (P <0.01), the pH was increased (P <0.05) in 23 of the 38 patients treated with NIPPV for 2 h, the effective rate was 63.2% 38). The cause of AECOPD, interstitial pneumonia, acute left heart failure and pulmonary infection in patients with significant effect; and the cause of bronchial asthma, lung cancer, ARDS and MOF patients with poor response. The success rate of type Ⅰ respiratory failure was 40.0% (6/15), type Ⅱ respiratory failure was 78.5% (18/23), and the success rate of NIPPV for type Ⅱ respiratory failure was significantly higher than that of type Ⅰ respiratory failure (P0.01) . Conclusion: NIPPV is effective in emergency treatment of acute respiratory failure and should be used to improve the curative effect.