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间充质干细胞(mesenchymal stem cells,MSCs)是当前干细胞研究的热点之一。目前,皮肤愈合正逐渐受到重视。现有的研究认为骨髓间充质干细胞(BM-MSCs)能从多个方面促进皮肤愈合,如促进表皮生长、促进真皮成纤维细胞的增生等。皮肤间充质干细胞(SMSCs)和BM-MSCs均为MSCs,具有很多的相似性,且SMSCs较BM-MSCs更容易得到。所以可从目前对BM-MSCs的研究预测到SMSCs在皮肤创伤愈合中的研究前景,且将来很可能会替代BM-MSCs。
Mesenchymal stem cells (MSCs) are one of the hot spots in current stem cell research. At present, skin healing is gradually receiving attention. Existing research suggests that bone marrow mesenchymal stem cells (BM-MSCs) can promote skin healing in many aspects, such as promoting epidermal growth and promoting the proliferation of dermal fibroblasts. Both mesenchymal stem cells (SMSCs) and BM-MSCs are MSCs with many similarities, and SMSCs are more accessible than BM-MSCs. Therefore, the current research on BM-MSCs predicts the research prospects of SMSCs in skin wound healing and may replace BM-MSCs in the future.