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目的:对艾滋病合并沙门氏菌感染临床特征进行探讨和分析,为患者的临床诊断及用药提供指导。方法:选取我院于2012年1月-2014年10月期间收治的20例艾滋病合并沙门氏菌感染患者,对其临床资料进行回顾式分析,患者的临床症状有发热、腹痛、腹泻等,对患者血液、骨髓和粪便进行沙门氏菌培养,并采用抗生素进行治疗。结果:沙门氏菌主要发生于CD4T淋巴细胞少于200个/ul的患者当中,经沙门氏菌的培养,患者的血液、骨髓或大便的沙门氏菌培养均为阳性,血液及骨髓培养出沙门氏菌共14例,占70%,粪便培养出沙门氏菌6例,占30%,患者经过治疗后,感染得到控制,病情好转。结论:艾滋病合并沙门氏菌感染患者的临床表现多为菌血症,需要依靠细菌培养才能确诊,患者一旦感染沙门氏菌,必须尽早诊断,并积极进行治疗。
Objective: To investigate and analyze the clinical features of AIDS-associated Salmonella infection and provide guidance for the clinical diagnosis and medication of patients. Methods: Twenty patients with AIDS-associated Salmonella infection in our hospital from January 2012 to October 2014 were retrospectively analyzed. The clinical symptoms of the patients were fever, abdominal pain, diarrhea and so on. The patients’ blood , Bone marrow and feces Salmonella culture, and the use of antibiotics for treatment. Results: Salmonella mainly occurred in CD4T lymphocytes less than 200 / ul patients, Salmonella culture, the patient’s blood, bone marrow or stool Salmonella culture were positive, the blood and bone marrow Salmonella cultured a total of 14 cases, accounting for 70 %, Salmonella cultured in feces 6 cases, accounting for 30%, after treatment of patients, the infection was controlled, the condition improved. Conclusions: The clinical manifestations of AIDS patients with Salmonella infection are mostly bacteremia. Bacterial cultures should be used to confirm the diagnosis. Once the patients have been infected with Salmonella, they must be diagnosed as soon as possible and actively treated.