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抗精神病药物可引起各种锥外系副反应,如急性肌张力障碍、震颤、静坐不能或巴金森氏症候群。近年文献陆续报道长期用抗精神病药物后出现锥外系另一副反应,称“迟发性运动障碍”或“迟发性运动不协调”为这类药物最严重的合并症之一。1957年Schon—cker首先加以描述。迟发性运动障碍系指患者在长期大剂量用抗精神病药物治疗中或突然的停用抗精神病药物治疗后出现的重复、不自主、刻板和有节律但并非完全不可逆的异常运动。其特点是口面部、肢体和躯干肌的不自主运动,临床也称为口—舌—咀嚼(Bucco—Linguo—Mas—ticatory,BLM)运动不能三联症。有人报道精神分
Antipsychotic drugs can cause a variety of extrapyramidal side effects, such as acute dystonia, tremor, meditation can not or Parkinson’s syndrome. In recent years, the literature has reported another long-term use of antipsychotics outside the cone after another reaction, saying that “delayed dyskinesia” or “delayed motor uncoordinated” for these drugs one of the most serious complications. Schon-cker first described it in 1957. Tardive dyskinesia refers to repetitive, involuntary, stereotyped and rhythmic but not completely irreversible abnormalities that occur in patients after long-term high-dose antipsychotics or sudden anti-psychotreatment. It is characterized by involuntary movements of the mouth and face, body and trunk muscles. Clinically, it is also referred to as Bucco-Linguo-Mas-ticatory (BLM). Someone reported mental points