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本文测定51例未经治疗的和42例经过抗甲状腺药物治疗的甲状腺机能亢进症(简称甲亢)病人血清T_3、T_4和3,3’,5’—三碘甲腺原氨酸(简称rT_3)。结果未经治疗的甲亢病人血清T_3、T_4和rT_3与正常人比较有显著增高。其中血清rT_3与T_3、T_4呈正相关。其平均含量与正常人比较:T_3高3~5倍,T_4高2~4倍,rT_3高4~6倍。三者对甲亢的诊断符合率分别为:96、08%、82、30%和90、19%。24例经过抗甲状腺药物治疗的甲克病人血清T_3、T_4恢复正常,rT_3也明显降低。本文结果提示:rT_3可以作为甲亢诊断和治疗的良好指标。其敏感度高于T_3、T_4,诊断符合率也高于T_4,但低于T_3。
In this paper, 51 cases of untreated and 42 cases of anti-thyroid drugs after treatment of hyperthyroidism (referred to as hyperthyroidism) serum T_3, T_4 and 3,3 ’, 5’-triiodothyronine (referred to as rT_3) . Results The serum levels of T_3, T_4 and rT_3 in patients with untreated hyperthyroidism were significantly higher than those in normal controls. Serum rT_3 was positively correlated with T_3 and T_4. The average content of normal compared with: T_3 high 3 to 5 times, T_4 high 2 to 4 times, rT_3 high 4 to 6 times. The three coincidence rates of diagnosis of hyperthyroidism were: 96,08%, 82,30% and 90,19%. 24 cases of anti-thyroid drug-treated patients with Keto serum T_3, T_4 returned to normal, rT_3 also significantly decreased. The results suggest that: rT_3 can be used as a good indicator of diagnosis and treatment of hyperthyroidism. The sensitivity is higher than T_3, T_4, diagnostic coincidence rate is higher than T_4, but lower than T_3.