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目的 研究淋巴免疫化疗对进展期胃癌的治疗作用。方法 实验组 :术前经内镜胃粘膜下注射加手术时胃浆膜下注射化疗药及生物制剂与活性炭的混悬液。对照组 :术前经股动脉插管灌注化疗药及生物制剂的水溶液 (检测治疗前后外周血细胞免疫功能指标 )。结果 淋巴免疫化疗后 ,两组外周血细胞免疫功能之间的差异有显著性 ( P <0 .0 5 )。结论 经淋巴途径的免疫化学治疗能促进淋巴转移癌细胞凋亡的发生 ,提高机体的免疫功能。
Objective To study the therapeutic effect of lymphoid immunotherapy on advanced gastric cancer. Methods Experimental group: preoperative gastric endoscopic submucosal injection plus surgery subserosal chemotherapy drugs and biological agents and activated carbon suspension. Control group: preoperative perfusion through the femoral artery chemotherapeutic drugs and biological agents in aqueous solution (before and after treatment to detect peripheral blood cell immune function indicators). Results There was a significant difference in cellular immune function between the two groups after lymphatic chemotherapy (P <0.05). Conclusion Immunochemotherapy through the lymphatic route can promote the apoptosis of lymphatic metastatic cancer cells and improve the immune function.