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目的评价探究性眼动分析(EEM)和事件相关电位(ERP)对军人创伤后应激障碍患者认知功能评估的临床价值。方法采用EEM和ERP对某三级甲等部队医院心理科收治的96例创伤后应激障碍官兵(研究组)和随机抽取某部100名官兵(对照组)进行测定,并将结果进行比较。结果①军人创伤后应激障碍患者EEM凝视点数(NEF)、反应探索评分(RSS)及D值与对照组相比,两者差异有统计学意义(P<0.01);②军人创伤后应激障碍患者ERP测定,N2、P3波潜伏期较对照组延长,P3波幅较对照组降低,其差异比较均有显著性意义(P<0.01);③相关分析显示,研究组N2、P3波潜伏期与NEF、RSS呈负相关(r=-0.19~-0.42,P<0.05或0.01),与D值呈正相关(r=0.30,0.48;P<0.01);P3波幅与NEF、RSS呈正相关(r=0.38,0.51;P<0.01),与D值呈负相关(r=-0.32,P<0.01)。结论 EEM和ERP测定具有良好的一致性,可作为判断军人创伤后应激障碍患者认知功能的重要指标。
Objective To evaluate the clinical value of exploratory eye movement analysis (EEM) and event related potentials (ERP) in the assessment of cognitive function in military patients with posttraumatic stress disorder. Methods Ninety-six post-traumatic stress disorder officers and soldiers (study group) and 100 officers and soldiers (control group) randomly selected from the psychology department of a third-class A-level hospital were measured by EEM and ERP, and the results were compared. Results ① Compared with the control group, there were significant differences in EEM fixation score (NEF), reaction probing score (RSS) and D value between the military and the control group (P <0.01); ② The post-traumatic stress The latency of N2 and P3 wave in patients with disorder was longer than that in control group, and the amplitude of P3 was lower than that in control group (P <0.01). (3) The correlation analysis showed that the latency of N2 and P3 wave in study group was significantly correlated with NEF (R = -0.19 ~ -0.42, P <0.05 or 0.01), and had positive correlation with D value (r = 0.30,0.48; P <0.01). The amplitude of P3 was positively correlated with NEF and RSS , 0.51; P <0.01), and negatively correlated with D value (r = -0.32, P <0.01). Conclusion The EEM and ERP have good consistency, which can be used as an important index to judge the cognitive function of soldiers in post-traumatic stress disorder.