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目的 探讨铝碳酸镁与西沙必利联合治疗胆汁反流性胃炎的临床效果。方法 对 15 0例胆汁反流性胃炎随机分成实验组 10 0例 ,对照组 5 0例 ,分别给予铝碳酸镁与西沙必利及硫糖铝片与西沙必利联合治疗 ,疗程为 4周 ,治疗期间内镜复查 ,并观察腹痛、腹胀、恶心及呕吐胆汁等症状变化 ,其结果经统计学分析。结果 治疗后总有效率分别为 10 0 %和 82 % ,两组比较差异有显著意义 (P =0 0 0 0 1)。结论 铝碳酸镁与西沙必利联合治疗 ,具有结合胃内胆酸 ,保护胃粘膜 ,增强胃排空 ,阻止胆汁反流 ,从而促进胆汁反流性胃炎的病理愈合 ,有效缓解胆汁反流性胃炎的症状 ,是治疗胆汁反流性胃炎的有效药物。
Objective To investigate the clinical effect of combination of aluminum magnesium carbonate and cisapride in the treatment of bile reflux gastritis. Methods Fifty cases of bile reflux gastritis were randomly divided into experimental group (100 cases) and control group (50 cases). The patients were given combined treatment of aluminum magnesium carbonate, cisapride and sucralfate respectively with cisapride for 4 weeks. Endoscopy during treatment, and observed abdominal pain, abdominal distension, nausea and vomiting bile and other symptoms, the results of statistical analysis. Results The total effective rates after treatment were 100% and 82%, respectively, with significant difference between the two groups (P = 0.00001). Conclusion Combined treatment of aluminum magnesium carbonate and cisapride, with the combination of gastric acid in the stomach, protect the gastric mucosa, enhance gastric emptying and prevent bile reflux, thereby promoting pathological healing of bile reflux gastritis, effectively relieve bile reflux gastritis The symptoms of bile reflux gastritis is an effective drug.