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昆布为海带科植物海带Laminaria japonicaAresch,既是食物,又是药物。它有消痰软坚,利水消肿的功能。资料表明它除了降压、消炎等作用外,还有降脂的作用。临床上大多以方剂使用,单味药应用较少。对于有效部位的研究更为少见。本文以昆布的不同溶剂提取物对大鼠高脂血症作降脂实验,探讨昆布降脂作用的有效部位,为药物的研究和生产利用作参考。材料与方法一、药物的提取和分离昆布由本院药厂提供。按常规方法将药材剪碎后分别用乙醚、药用乙醇和水作溶剂,热提后制得乙醚提取物,乙醇提取物和水提取物三部分。
Kelp is Laminaria japonica Aresch, a kelp plant that is both a food and a drug. It has the function of eliminating phlegm and strengthening the body and reducing swelling. The data shows that in addition to blood pressure, anti-inflammatory and other effects, there are lipid-lowering effects. Most of the clinical use of prescriptions, a single herb application is less. Research on effective sites is rarer. In this paper, lipid extracts of hyperlipidemia in rats were treated with different solvent extracts of kelp, and the effective part of the lipid-lowering effect of kelp was explored, which was used as reference for the research, production and utilization of the drug. Materials and Methods 1. Extraction and Separation of Drugs Kelp was provided by our hospital. After the medicinal material was crushed by conventional methods, ethyl ether, medicinal ethanol and water were used as solvents, respectively, and the ether extract, the ethanol extract and the water extract were prepared in three parts by heat extraction.