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目的评价静脉注射西地兰治疗心功能正常的阵发性心房颤动,维持窦性心律的长期疗效。方法静脉推注西地兰100～120mg于30min内,而后继以每300μg/min持续滴注,24h内可使87%患者转复为窦性心律。结果治疗24h后,静脉注射西地兰转为窦性心律者占87%;1h之内未能转为窦性心律者,其心室率平均下降30次/min(20%),使患者临床症状迅速缓解.结论方法疗效确切安全,无严重不良反应,在心电血压监测下可推广应用。
Objective To evaluate the long-term efficacy of intravenous injection of cedilanid in the treatment of paroxysmal atrial fibrillation with normal cardiac function. Methods Intravenous injection of cedilanid 100 ~ 120mg within 30min, followed by every 300μg / min continuous infusion, 24h can make 87% of patients converted to sinus rhythm. Results After treatment for 24 h, 87% of patients were converted to sinus rhythm by intravenous injection of cedilanid; those who failed to convert to sinus rhythm within 1 hour had an average decrease in ventricular rate of 30 beats / min (20%), resulting in clinical symptoms Quickly relieve.Conclusion The method is safe, without serious adverse reactions, can be widely applied in the monitoring of ECG.