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本发明属于兽药制备技术领域,具体涉及一种用于兽药残留检测的卡巴氧残留标志物喹噁啉-2-羧酸的合成方法。其制备步骤包括:1)以邻苯二胺为原料,与丙酮醛缩合,即得中间产物2-甲基喹噁啉;2)将所得中间体2-甲基喹噁啉用二氧化硒进
The invention belongs to the technical field of veterinary drug preparation, in particular to a synthesis method of quinacarboline-2-carboxylic acid which is a residue of carbachol for veterinary drug residue detection. The preparation steps include: 1) o-phenylenediamine as a raw material, and pyruvaldehyde are condensed to obtain an intermediate 2-methylquinoxaline; 2) the obtained intermediate 2-methylquinoxaline is oxidized with selenium dioxide