报道新型强心药咪苯甲嗪酮(CI-930)合成。参考有关文献采用了新路线并改进了一些反应的条件和方法,使操作简便合理,收率有所提高。药理实验结果表明它具有明显的抗血栓作用,并选择性抑制血栓素A_2的合成。对开发新的血栓素合成酶抑制剂和防治血栓栓塞性脑心血管疾病具有较重要的理论意义和应用价值。 A new cardiac drug, imidamezinone (CI-930), was reported. Reference to the literature using a new route and improve the conditions and methods of some of the reaction, the operation is simple and reasonable, the yield has increased. Pharmacological results show that it has obvious antithrombotic effect, and selectively inhibit the synthesis of thromboxane A_2. The development of new thromboxane synthase inhibitors and prevention and treatment of thromboembolic cerebrovascular disease have more important theoretical and practical value.