主要完成人员:李琦涵、刘龙丁、谢忠平、莫兆军、董承红等主要完成单位:中国医学科学院医学生物学研究所、广西疾病预防控制中心该项目主要内容和创新点:首次利用自主分离我国流行毒株及人源化细胞成功研制出全球首个具有完全自主知识产权的手足口病疫苗;唯一采用人二倍体细胞作为疫苗制备 Major Completed Personnel: Mainly accomplished by Li Qihan, Liu Longding, Xie Zhongping, Mo Zhajun, Dong Chenghong etc. Main institutes: Institute of Medical Biology, Chinese Academy of Medical Sciences and Guangxi Center for Disease Control and Prevention Main Contents and Innovations: For the first time, Strain and humanized cells successfully developed the world’s first hand-foot-mouth disease vaccine with completely independent intellectual property rights; the only use of human diploid cells as a vaccine preparation