肝脏在药物代谢中起着重要的作用,大多数药物在肝内经过生物转化作用而清除。近年来,随着药物种类的不断增多,药物性肝损害的发生率也相应增加。据统计,药物性肝病可占所有黄疸住院患者中的2%～5%,或“急性肝炎”住院患者中的10%。而在老年肝病患者中,药物性肝病的比例更 The liver plays an important role in drug metabolism, and most drugs are cleared in the liver through bioconversion. In recent years, with the increasing types of drugs, the incidence of drug-induced liver damage also increased accordingly. According to statistics, drug-induced liver disease can account for 2% to 5% of all hospitalized patients with jaundice or 10% of hospitalized patients with acute hepatitis. In elderly patients with liver disease, the proportion of drug-induced liver disease is more