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目的探讨基层医院高危人工流产后口服雌孕激素的疗效。方法将400例高危人工流产患者分成两组,对照组200例,常规口服抗生素预防感染处理;实验组200例,在常规治疗同时给予戊酸雌二醇3 mg,1次/d,连服21 d,后半周期加服安宫黄体酮10 mg,1次/d,共10 d,序贯治疗3个周期;比较治疗3个月后月经量情况,宫腔镜下宫腔粘连发生率。结果实验组月经量优于对照组(P<0.05),实验组宫腔粘连发生率较对照组低(P<0.01)。结论高危妊娠术后口服雌孕激素可促进月经恢复及子宫内膜恢复,降低宫腔粘连发生率,宜在基层医院推广应用。
Objective To investigate the efficacy of oral estrogen and progesterone after high-risk induced abortion in primary hospitals. Methods 400 cases of high-risk abortion patients were divided into two groups, the control group of 200 cases, routine oral antibiotics to prevent infection; experimental group of 200 cases, given routine administration of estradiol valerate 3 mg, 1 / d, and even served 21 d, the second half of the cycle plus escitalopram 10 mg, 1 / d, a total of 10 d, sequential treatment of three cycles; Results The menstrual volume in the experimental group was significantly higher than that in the control group (P <0.05). The incidence of intrauterine adhesions in the experimental group was lower than that in the control group (P <0.01). Conclusions Oral estrogen and progesterone after high-risk pregnancy can promote menstruation recovery and endometrium recovery and reduce the incidence of intrauterine adhesions, which should be popularized and applied in primary hospitals.