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目的分析超声定量检测T2DM患者肝脏脂肪含量(LFC)和各临床资料及血脂组分的相关性。方法采用超声定量检测306例住院T2DM患者LFC,分别记录性别、年龄、体重、BMI、WC、臀围(HC)、WHR及病程等临床资料,并检测TC、TG、HDL-C、LDL-C,根据LFC三分位分为Q1~Q3组,分析其与各临床资料及血脂组分的相关性。结果随LFC增加,各组体重、BMI、WC、HC、WHR、TG均逐步增加,而年龄和病程逐步递减(P<0.05)。校正性别、年龄、BMI后,偏相关分析显示,LFC与TG呈线性正相关(r=0.216,P=0.000)。结论 T2DM患者超声定量检测LFC对非酒精性脂肪性肝病诊治有一定的临床应用价值,其与体重、BMI、WC、HC、WHR有关,与血清TG水平呈正相关。
Objective To analyze the correlation between liver fat content (LFC) and clinical data and serum lipid components in T2DM patients by quantitative ultrasound. Methods Totally 306 patients with T2DM admitted to hospital were enrolled in this study. The clinical data of sex, age, body weight, BMI, WC, hip circumference (WHR) and duration of disease were recorded and the levels of TC, TG, HDL- , According to LFC tertile divided into Q1 ~ Q3 group, analyze its correlation with each clinical data and blood lipid components. Results With the increase of LFC, the body weight, BMI, WC, HC, WHR and TG increased gradually in all groups, but gradually decreased in age and duration (P <0.05). After adjusting for sex, age, and BMI, partial correlation analysis showed a positive linear correlation between LFC and TG (r = 0.216, P = 0.000). Conclusions Ultrasound quantitative detection of LFC in T2DM patients has some clinical value in the diagnosis and treatment of non-alcoholic fatty liver disease, which is related to body weight, BMI, WC, HC and WHR, and positively correlated with serum TG level.