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目的:优选复方洋参益智片部分药材的提取工艺。方法:采用回流醇提法,HPLC测定阿魏酸含量,以阿魏酸含量为检测指标,选取乙醇体积分数、乙醇用量、提取次数为考察因素,通过L9(34)正交试验法优选复方洋参益智片提取工艺。结果:最佳提取工艺为加8,6倍量70%乙醇提取2次,每次提取时间1.5 h。结论:优化的复方洋参益智片提取工艺稳定可行。
Objective: To optimize the extraction process of some medicinal materials of compound ginseng puzzle. Methods: The content of ferulic acid was determined by refluxing alcohol and HPLC. The content of ferulic acid was taken as the detection index. The volume fraction of ethanol, the amount of ethanol and the number of extraction were taken as the investigation factors. The optimum conditions were as follows: L9 (34) Participation benefit tablets extraction process. Results: The best extraction process was adding 8, 6 times the amount of 70% ethanol extraction twice, each extraction time of 1.5 h. Conclusion: The optimized compound ginseng puzzle extraction process is stable and feasible.