A low-cost β type Ti-1.5Fe-6.8Mo-4.8Al-1.2Nd (mass fraction, %)(T12LCC) alloy was produced by blended elemental powder metallurgy(P/M) method and subsequent thermomechanical treatment. Low cycle fatigue(LCF) behavior of P/M T12LCC alloy before and after thermomechanical treatment was studied. The results show that the LCF resistance of P/M titanium alloy is significantly enhanced through the thermomechanical treatment. The mechanisms for the improvement of LCF behavior are attributed to the elimination of residual pores, the microstructure refining and homogenization. A low-cost β type Ti-1.5Fe-6.8Mo-4.8Al-1.2Nd (mass fraction,%) (T12LCC) alloy was produced by blended elemental powder metallurgy (P / M) method and subsequent thermomechanical treatment. (LCF) behavior of P / M T12LCC alloy before and after thermomechanical treatment was studied. The results show that the LCF resistance of P / M titanium alloy is significantly enhanced through the thermomechanical treatment. The mechanisms for the improvement of LCF behavior are attributed to the elimination of residual pores, the microstructure refining and homogenization.