糖尿病自主神经病变(diabetic autonomic neuropathy,DAN)是一组由自主神经功能和(或)结构受损引发的征候群,主要累及心血管、胃肠道和泌尿生殖系统,具有起病隐匿、逐渐进展、可于症状出现前发生、甚少自行缓解的临床特征。其中,糖尿病心脏自主神经病变(diabetic cardiac autonomic neuropathy,DCAN)危害尤为严重,可以引起无痛性心肌缺血、心肌梗死及恶性心律失常甚至心源性猝死,从而引起医学工作者广泛关注。 Diabetic autonomic neuropathy (DAN) is a group of syndromes caused by impaired autonomic nerve function and / or structure, mainly involving the cardiovascular, gastrointestinal and genitourinary systems, with occult onset and gradual progress , Before the onset of symptoms, rarely relieve the clinical features. Among them, diabetic cardiac autonomic neuropathy (DCAN) is particularly harmful and causes painless myocardial ischemia, myocardial infarction, malignant arrhythmia and even sudden cardiac death, which cause widespread concern for medical workers.