Objective: To systematically evaluate the efficacy and safety of Fuke Qianjin Tablets (妇科 千金片) in the treatment of chronic pelvic inflammation. Methods: A systematically and comprehensively search was conducted in 4 Chinese databases of CNKI, VIP, WanFang and CBM and the foreign language databases of Pubmed, EMbase and The Cochrane Library. The retrieval time was from database establishment to March 2019. The randomized controlled trials of Fuke Qianjin Tablets (妇科千金片) in the treatment of chronic pelvic inflammation were selected according to the predetermined criteria. The quality of the included study was evaluated by Cochrane collaborative network bias risk evaluation tool, and the meta-analysis was performed by RevMan5.3 software. Results: A total of 1009 related literatures were searched. After initial screening and strict evaluation, 55 studies were included, with a total sample size of 6826 cases, including 3416 cases in the experiment group and 3410 cases in the control group. The results of meta-analysis showed that the total effective rate of Fuke Qianjin Tablets (妇科千金片) combined with antibiotics in the treatment of chronic pelvic inflammation was better than that of antibiotics alone (RR=1.20, 95％ CI [1.17, 1.22], P<0.00001). Fuke Qianjin Tablets (妇科千金片) combined with antibiotics was better than that of antibiotics alone in the improvement of abdominal pain symptoms (RR=1.40, 95％ CI [1.04, 1.88], P<0.00001), leukorrhea abnormality (RR=1.38, 95％ CI [1.16, 1.65], P<0.0004). In terms of safety, Fuke Qianjin Tablets (妇科千金片) combined with antibiotics could reduce the incidence of adverse reactions (RR=0.67, 95％ CI [0.48, 0.93], P<0.02). The main adverse reactions were nausea and vomiting, bittess and astringency in the mouth, rash and so on. All of them could be tolerated and the symptoms could disappear in the short term, and had no effect on the treatment. Conclusion: Fuke Qianjin Tablets (妇科千金 片) combined with antibiotics in the treatment of chronic pelvic inflammation can improve the total effective rate, relieve abdominal pain and abnormal leukorrhea and other clinical discomfort symptoms, improve the quality of life of patients to a certain extent, and no serious adverse reactions are found. Due to the limitation of the quality and quantity of the included literature, the above conclusions need to be further studied and verified by high-quality research.