~3H-氧乐果静脉给予大鼠后,放射性核素比活度在肾脏最高,肝脏和甲状腺次之,脂肪最低;在甲状腺内生物半减期最长(为 110.88小时);在各组织和器官中存留高峰时间均在给药后1小时;能较迅速进入脑、睾丸、卵巢及胎鼠体内;可经尿、粪及乳汁排泄,以尿为主要排泄途径。给药后24、48、72及96小时,尿中排泄率分别为30.95、2.79、1.40及0.62％,粪分别为9.29、0.80、0.33及0.03％。192 小时内尿和粪共累积排出 47.94％。 ~ 3H-omethoate after intravenous administration, the radionuclide specific activity in the kidney highest, followed by the liver and thyroid, the lowest fat; the longest in the thyroid biological half-life reduction (110.88 hours); in each tissue and The peak time of organ preservation is 1 hour after administration; it can enter into the brain, testis, ovary and fetal rat more rapidly; it can be excreted by urine, feces and milk, with urine as the main excretion pathway. At 24, 48, 72 and 96 hours after administration, urinary excretion rates were 30.95, 2.79, 1.40 and 0.62%, and feces were 9.29, 0.80, 0.33 and 0.03%, respectively. Urine and faeces accumulated 47.94% in 192 hours.