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Not only high spectral efficiency (SE) but also high energy efficiency (EE) are required for future wireless communication sys-tems. Radio orbital angular momentum (OAM) provides a new perspective of mode multiplex-ing to improve SE. However, there are few studies on the EE performance of OAM mode multiplexing. In this paper, we investigate the SE and EE of a misaligned uniform concentric circle array (UCCA)-based multi-carrier multi-mode OAM and multiple-input multiple-output (MCMM-OAM-MIMO) system in the line-of-sight (LoS) channel, in which two transceiver architectures implemented by radio frequency (RF) analog synthesis and baseband digital synthesis are considered. The distance and an-gle of arrival (AoA) estimation are utilized for channel estimation and signal detection, whose training overhead is much less than that of tra-ditional MIMO systems. Simulation results val-idate that the UCCA-based MCMM-OAM-MI-MO system is superior to conventional MIMO- OFDM system in the EE and SE performances.