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静脉注射大肠杆菌内毒素造成家兔内毒素休克模型。电镜观察其主要脏器超微结构的结果:心肌细胞的肌膜向外发出许多细长绒毛样突起,肌丝排列紊乱、断裂,并可出现肌纤维溶解消失等变化。毛细血管内皮形成许多边缘突伸向腔内。神经细胞的粗面内质网常有脱颗粒、囊扩张现象。在心肌与神经细胞内均可见到线粒体肿胀、嵴排列紊乱、结构破坏,及形状、大小差异较大的现象。肾近曲小管细胞的胞质内有大量溶酶体。
Intravenous injection of E. coli endotoxin causes endotoxic shock in rabbits. Electron microscopy of the ultrastructure of the main organs of the results: the myocardial cells of the sarcolemma issued many elongated villous projections, myofilaments arranged disorder, fracture, and dissolution of muscle fibers may disappear and other changes. Many of the capillary endothelial cells protrude into the lumen. Rough endoplasmic reticulum of nerve cells often degranulation, capsule expansion phenomenon. In the myocardium and nerve cells can be seen in the mitochondria swelling, ridge disorders arranged, structural damage, and the shape, size, larger differences. There are a large number of lysosomes in the cytoplasm of renal proximal tubule cells.