溃疡性结肠炎(ulcerative colitis,UC)是一种发生在胃肠道的慢性非特异性UC。临床主要表现为腹泻、黏液便、脓血便、腹痛、里急后重等;其特点是症状反复发作,迁延不愈,严重影响患者生活质量。UC的发病机制不明确,目前诊断主要依靠临床表现、内镜、组织学、影像学和实验室检查。但是由于缺乏灵敏性和特异性高的诊断指标,疾病处于进展期的诊断往往延迟[1-2]。UC的发病存在东西方差 Ulcerative colitis (UC) is a chronic, nonspecific UC that occurs in the gastrointestinal tract. The main clinical manifestations of diarrhea, mucus, pus and blood will, abdominal pain, tenesmus and other; characterized by recurrent symptoms, prolonged unhealed, seriously affecting the quality of life of patients. The pathogenesis of UC is not clear, the current diagnosis depends mainly on clinical manifestations, endoscopy, histology, imaging and laboratory tests. However, due to the lack of sensitive and specific diagnostic criteria, the diagnosis of advanced disease is often delayed [1-2]. The incidence of UC there are differences between east and west