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目的探讨染色体异常与男性不育的关系。方法对994例男性不育患者进行染色体核型检测与分析。结果发现染色体异常132例,异常率为13.27%;其中性染色体异常66例,占异常核型的50%;常染色体异常66例,占异常核型的50%。结论染色体异常是造成男性不育的重要遗传因素,对有不育症患者的男性进行染色体检查,有助于病因的诊断。且提示一些常染色的异常与男性无精子症有关。
Objective To investigate the relationship between chromosomal abnormalities and male infertility. Methods Nine hundred and ninety-nine male infertility patients were tested for chromosomal karyotypes. The results showed that 132 cases of chromosomal abnormalities, the abnormal rate was 13.27%; 66 cases of chromosomal abnormalities, accounting for 50% of anomalous karyotype; 66 cases of autosomal abnormalities, accounting for 50% of abnormal karyotype. Conclusions Chromosomal abnormalities are the important genetic factors causing male infertility. Chromosome examination of male infertility patients is helpful to the diagnosis of etiology. And suggest some anomalies associated with male azoospermia.