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目的探讨幽门螺杆菌阳性(Hp+)的消化性溃疡(PU)愈合和复发的物理治疗(毫米波mmW)及其联合药物治疗的前景.方法本组PU93例采用mmW辐射探头对PU患者体表胃投影区照射30min,(n=50)每日1~2次,联合药物(甲哨唑+西咪替丁)在Hp+的PU愈合和复发的疗效进行研究,并与对照组43例进行比较.结果mmW治疗及联合药物治疗组与对照组单用药物H2受体阻滞剂西咪替丁相比较,结果治疗组溃疡愈合率及Hp根除率100%(50/50)及98%(49/50).1年后复发率为4%(2/50);而对照组溃疡愈合率905%(38/43),Hp根除率508%(25/43),1年后复发率209%(9/43).说明Hp根除与溃疡复发有一定关系,2组相比有显著差异(P<005~001).结论mmV联合药物治疗Hp+PU愈合和复发优于单用H2受体阻滞剂.
Objective To investigate the physical therapy (millimeter mmW) healing and relapse of Helicobacter pylori-positive (Hp +) peptic ulcer (PU) and its prospect of combination therapy. Methods The group of 93 cases of PU with mmW radiation probe were used to irradiate the surface of stomach in PU patients for 30 minutes (n = 50) once or twice a day. PU combined with drug (methotrexate + cimetidine) in Hp + The curative effect of recurrence was studied and compared with 43 cases in control group. Results Compared with the single drug H2 antagonist cimetidine in the treatment group and the control group, the healing rate of the ulcer and the rate of Hp eradication in the treatment group were 100% (50/50) and 98% (49%), respectively 50). The recurrence rate was 4% (2/50) after 1 year. In the control group, the healing rate of ulcer was 90.5% (38/43) and the eradication rate of Hp was 50.8% (25/43) 9% (9/43). Hp eradication shows a certain relationship with the recurrence of ulcers, two groups were significantly different (P <0 05 ~ 0 01). Conclusion The combination of mmV and Hp + PU is more effective than H2 alone in the healing and recurrence of Hp + PU.