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将3,6-二氯哒嗪-金鸡纳生物碱衍生物用于催化β-二羰基化合物与溴乙酰甲酸乙酯/β-取代的溴乙酰甲酸乙酯的不对称“中断的”Feist-Bénar y反应,得到了较高的化学产率(72%~97%)和最高达93%ee的立体选择性.
3,6-Dichloropyridazine-cinnamalkite alkaloid derivatives were used to catalyze the asymmetry of the β-dicarbonyl compound with ethyl bromoacetate / β-substituted ethyl bromoacetate “interrupted” Feist -Bénar y, resulting in higher stereochemical selectivity (72% -97%) and stereoselectivity up to 93% ee.