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农药、医药、兽药同为生理活性物质,其开发实质为新化学实体的开发。三药新化学实体具有使用功能拓展性、原料或中间体通用性、结构相似性、创制方法的相似性等相通性特点。指出三药协同开发已成一种趋势,可通过组合化学技术、新靶标发现及制备、高通量筛选技术、活性化合物库建设等专题的学术交流及相应资源的共建共享、引导研究人员扩大新药筛选范围等措施推动三药协同开发。
Pesticides, medicine, veterinary drugs with the same physiologically active substances, the development of the essence of the development of new chemical entities. Three new chemical entities have the use of functional extension of the nature of raw materials or intermediates, structural similarity, the similarity of creation methods and other characteristics of connectivity. It is pointed out that synergistic development of the three drugs has become a trend. The academic exchanges and corresponding resources co-construction and sharing can be conducted through combinatorial chemistry technology, discovery and preparation of new targets, high-throughput screening technology, and construction of an active compound library, so as to guide researchers to expand new drugs The scope of screening and other measures to promote the coordinated development of three drugs.