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睾丸是白血病髓外侵犯常见部位,并常是复发的首发部位。近年睾丸浸润的发病率逐渐增加,多数报告为16～22%。白血病确诊时,予示存在睾丸浸润的特征包括:年龄<2岁或>8岁,白细胞计数>2万/mm~3、血小板计数<3万/mm~3,纵膈肿块,肝、脾和/或淋巴结增大。本组共收治44例白血病睾丸侵犯的患儿,38例经组织学证实关于睾丸浸润局部和全身最适宜的治疗意见不一。SWOG 儿科的经验认为应对双侧睾丸放疗2500拉德,目的是控制局部病灶;并作为病程中的维持治疗。
Testicular leukemia is a common site of extramedullary violations, and often the starting site of recurrence. In recent years, the incidence of testicular infiltration gradually increased, the majority reported as 16 to 22%. The diagnosis of leukemia, showing the presence of testicular infiltration characteristics include: age <2 years or> 8 years old, white blood cell count> 20,000 / mm3, platelet count <30,000 / mm3, mediastinal mass, liver, spleen and / Or enlarged lymph nodes. This group received a total of 44 cases of leukemia testicular infants, 38 cases histologically confirmed the testicular infiltration of local and systemic treatment of the most appropriate disagreement. SWOG pediatric experience that should be treated with bilateral radiated testicular radiotherapy Radradius, the purpose is to control the local lesions; and as the duration of maintenance treatment.