睾丸酮可以促进受损舌下及面神经的再生和延长神经细胞的存活。但对两者作用的时限不同。在轴突切断后的前四周内给予睾丸酮可以促进神经再生,而在后五周内则可以减少神经细胞的死亡。为证实睾丸酮第一作用部位在效应肌而非神经元的设想,应用雄激素受体的阻断剂HF,检查其对睾丸酮神经营养性作用的影响。结果证明,HF可以完全消除睾丸酮对切断轴突的运动神经元所具有的促进存活作用。 Testosterone promotes the regeneration of damaged sublingual and facial nerves and prolongs the survival of nerve cells. But the time difference between the two roles is different. Administration of testosterone during the first four weeks after axotomy promoted neurogenesis and reduced neuronal death within the next five weeks. To confirm that the first site of testosterone is in effector muscle rather than neurons, we examined the effects of androgen receptor blockers, HF, on testosterone neurotrophic effects. The results show that HF ​​can completely eliminate testosterone on axonal motor neurons have the promotion of survival.