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锌对有机体的重要意义,最早是1968年Raulin发现的.锌用于治疗疾病始于埃及.1963年Prasad等首次报导了中东儿童缺锌的症状,近十余年世界各国深入研究了锌的生理、生物化学、药理作用、对儿童生长发育等影响,从而取得了新的认识.一、生理学和生物化学锌在体内主要以各种金属酶的形式存在,其余以蛋白质结合物的形式分布于体液内,而以离子状态存在者极少.锌在结构上十分接近硫氢基团,对锌具有多方面重要功能有决定性作用.锌参与蛋白质合成,又具有保护细胞线粒体、微粒体免遭过氧化,稳定细胞膜的作用.维持人的正常味觉、嗅觉功能、有利于创伤面修复愈合.早于1963年Prasad等人描述了中东的男孩患有生长缓慢、性腺机能低下、贫血等综合症状,经查具有上述症状男孩血浆锌值明显低于正常,证实为缺锌表现.
The significance of zinc to the organism was first discovered by Raulin in 1968. Zinc was used to treat the disease in Egypt. For the first time in 1963, Prasad et al reported the symptoms of zinc deficiency in Middle East children. In the past decade or so, , Biochemistry, pharmacological effects, the impact on children’s growth and development, and thus gained new understanding.A, physiology and biochemistry Zinc in the body mainly in the form of various metalloenzyme, the rest in the form of protein conjugates distributed in body fluids , And very few exist in ionic state.Zinc is structurally very close to the sulfhydryl group and plays a decisive role in many important functions of zinc.Zinc participates in protein synthesis and also protects mitochondria and microsomes from peroxidation , Stabilize the function of the cell membrane Maintaining the normal taste and olfactory function of the human body is beneficial to the healing of the wound surface As early as 1963 Prasad et al described the Middle East boy suffering from the symptoms of slow growth, hypogonadism and anemia, Plasma zinc levels in boys with these symptoms were significantly lower than normal, confirming zinc deficiency.