1 临床资料 小儿10例,男4例,女6例。年龄13个月～7岁,其中3例小儿伴有咽后壁溃疡,除2例消瘦、营养状态欠佳外,其余无明显全身症状。口腔粘膜有单发或多发溃疡,部分病例伴有反复呼吸道感染。余2例为成人(男、女各1例),其中一例成人口腔粘膜、软腭、硬腭及咽周有大片状广泛深在溃疡。全部病例每年复发三次以上,每次持续1～2周,均经多种抗菌素,维生素B_2及局部用药等常规治疗效果不好来我科诊治。免 1 clinical data 10 children, 4 males and 6 females. Aged 13 months to 7 years, of which 3 cases of children with pharyngeal wall ulcers, in addition to 2 cases of weight loss, poor nutritional status, the rest without obvious systemic symptoms. Oral mucosa single or multiple ulcers, some cases accompanied by recurrent respiratory tract infection. The remaining two cases of adult (male and female one case), of which one case of adult oral mucosa, soft palate, hard palate and pharyngeal have large flaky extensive ulcers. All cases relapse more than three times per year, each lasting 1 to 2 weeks, after a variety of antibiotics, vitamin B_2 and local treatment of conventional treatment is not good to our department diagnosis and treatment. Free