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目的观察淋巴瘤对主要器官的浸润情况。方法对沈阳军区总医院1996年1月至2000年12月死亡的42例淋巴瘤患者进行尸体解剖,观察主要器官的大体变化及病理变化。结果42例尸检病例中有39例观察到肺部病理变化,占92.8%,主要表现为胸腔积液、胸膜炎症、肺播散、肺萎缩、肺出血、肺内感染、肺充血及水肿等。24例观察到心脏病理变化,占57.1%,主要表现为心包积液、心包及心壁播散。还有14例发生胃肠道播散,占33.2%,主要表现为肠穿孔,包括阑尾炎穿孔、回肠坏死穿孔及回肠癌性溃疡穿孔。另外,有少数病例同时出现多种病理变化。结论淋巴瘤可发生肺部、心脏及胃肠道等多器官浸润,本研究有助于对淋巴瘤患者出现呼吸功能障碍、心功能不全、肠梗阻及其他胃肠道症状的解释,对淋巴瘤的诊治有一定的临床指导意义。
Objective To observe the infiltration of lymphoma on major organs. Methods 42 cases of lymphoma patients who died in Shenyang Military Region General Hospital from January 1996 to December 2000 were examined by autopsy to observe the general changes and pathological changes of major organs. Results Of the 42 autopsy cases, pathological changes were observed in 39 cases, accounting for 92.8%. The main manifestations were pleural effusion, pleural inflammation, lung dissemination, lung atrophy, pulmonary hemorrhage, pulmonary infection, pulmonary congestion and edema. 24 cases of pathological changes observed, accounting for 57.1%, mainly as pericardial effusion, pericardial and heart wall disseminated. There were 14 cases of gastrointestinal spread, accounting for 33.2%, mainly manifested as intestinal perforation, including appendicitis perforation, ileal necrosis perforation and perforation of the ulcer of the ileum. In addition, there are a few cases at the same time a variety of pathological changes. Conclusions Lymphoma can occur in multiple organs such as the lungs, heart and gastrointestinal tract. This study is helpful for the interpretation of respiratory dysfunction, cardiac insufficiency, intestinal obstruction and other gastrointestinal symptoms in patients with lymphoma. The diagnosis and treatment of a certain clinical significance.