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东当归(Angelica acutiloba Kitagawa)在日本汉方医药中是熟知的妇科药。已报道从其热水提取物中得到的果胶多糖具有致B-淋巴细胞有丝分裂活性,多克隆B细胞激活剂活性,抗艾氏腹水癌细胞活性,诱导干扰素活性和抗补体活性。用cetavlon(十六烷基三甲基溴化铵)法和DEAE-葡聚糖层析从东当归中得到多糖部位,每个多糖部位都由类似的成分组成,但上述的生物活性却由不同的水溶性多糖部位所致。本文介绍东当归中抗肿瘤多糖的纯化和鉴定。活性成分证实是一种阿拉伯半乳聚糖。东当归根的热水提取物用乙醇沉淀和透
East Angelica (Angelica acutiloba Kitagawa) is a well-known gynecological medicine in Kampo medicine in Japan. It has been reported that the pectin polysaccharides obtained from its hot water extract have mitogenic activity to B-lymphocytes, activity of polyclonal B cell activators, activity against Ehrlich ascites cancer cells, induction of interferon activity and complement activity. The polysaccharide fraction was obtained from East Angelica by cetavlon (cetyltrimethylammonium bromide) method and DEAE-dextran chromatography. Each polysaccharide fraction was composed of similar components, but the above biological activity was different. Due to the water-soluble polysaccharides. This article describes the purification and identification of antitumor polysaccharides from Angelica sinensis. The active ingredient proved to be an arabinogalactan. Dong Dong Root Water Extract with ethanol