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目的调查我省喉癌流行病学特征及影响喉癌预后的相关因素。为我省喉癌防治工作提供理论依据。方法对1995年～2005年哈尔滨医科大学附属第二医院耳鼻咽喉-头颈外科收治的1090例喉癌患者进行回顾性调查研究。结果喉癌发病男女比例为2.30:1,女性喉癌发病率较其他地区高。在年龄分布中,50～69岁患者占68.9%。城市居民比农村居民发明率偏高,是农民的1.37倍,在职业方面以工人最多。吸烟量越大、吸烟时间越长,患喉癌的例数越多。正常人与喉癌患者ABO血型构成比之间无显著差异。声门上型喉癌占喉癌总数的58.53%,病理分型中鳞状细胞癌占96.25%。声门上型及喉咽癌颈淋巴结转移明显偏高。结论我省喉癌发病女性患者较其他地区多,且以声门上型最显著。50～69岁年龄段发病最高。吸烟与喉癌的发生有一定关系。城市居民比农村居民发病率高。喉癌发病与ABO血型无明显关系。
Objective To investigate the epidemiological characteristics of laryngeal cancer in our province and the related factors that affect the prognosis of laryngeal cancer. Provide a theoretical basis for the prevention and treatment of laryngeal cancer in our province. Methods A retrospective investigation was performed on 1090 laryngeal cancer patients admitted to otolaryngology - head and neck surgery department of the Second Affiliated Hospital of Harbin Medical University from 1995 to 2005. Results The incidence of laryngeal cancer was 2.30: 1, and the incidence of laryngeal cancer was higher in women than in other regions. In the age distribution, patients aged 50 to 69 accounted for 68.9%. Urban residents had higher rates of invention than rural residents, 1.37 times those of peasants, and the largest number of workers in employment. The greater the amount of smoking, smoking longer, the more cases of laryngeal cancer. There was no significant difference in ABO blood group constitution between normal and laryngeal cancer patients. Glottic laryngeal cancer accounted for 58.53% of the total number of laryngeal cancer, squamous cell carcinoma in pathological type accounted for 96.25%. Supraglottic and hypopharyngeal carcinoma neck lymph node metastasis was significantly higher. Conclusion The incidence of laryngeal cancer patients in our province more than in other areas, and the glottis type the most significant. The highest incidence of 50 to 69 age group. Smoking and the occurrence of laryngeal cancer have a certain relationship. Urban residents have a higher incidence than rural residents. The incidence of laryngeal cancer and ABO blood type no significant relationship.