近年来,经单鼻孔一蝶窦入路切除垂体腺瘤的手术方式不断普及,但其中的许多观念和技巧不甚一致,甚至有些可能还不够成熟。本文就手术相关问题进行综述。一、经单鼻孔-蝶窦手术治疗垂体腺瘤的历史与现状1987年,Griffith首先采用单鼻孔-蝶窦直接入路切除垂体腺瘤,由于其操作相对简单,且避免了传统唇下经蝶入路创伤大的缺点,被各国学者广泛采用。随着神经导航及神经内镜 In recent years, the single nostril and sphenoid sinus approach to surgical removal of pituitary adenoma continues to popularize, but many of the concepts and techniques are not consistent, and some may not mature enough. This article reviews the issues related to surgery. First, the single nostril - sphenoid sinus surgery history and status of pituitary adenoma 1987, Griffith first single-nostril - sphenoid sinus pituitary adenoma direct approach, due to its relatively simple operation, and to avoid the traditional lip-and-butterfly Pathology trauma shortcomings, widely used by scholars in various countries. With neuro navigation and neuroendoscopy