食管癌是一常见、多发性恶性肿瘤 ,尤以我国北方太行山区发病率最高。流行病学和病理学研究提示食管癌是一个多阶段、进行性发展过程 ;分子生物学研究发现组织细胞中有Ｐ53、Ｒｂ及ｒａｓ等基因的突变及在食管癌不同阶段的表达。吴教授对食管癌遗传学的研究发现 :食管癌患者 Esophageal cancer is a common and multiple malignancy, especially in the Taihang Mountain area in northern China. Epidemiological and pathological studies suggest that esophageal cancer is a multi-stage, progressive process; molecular biology studies have found mutations in genes such as P53, Rb and ras in tissue cells and expression in different stages of esophageal cancer. Prof. WU Wei’s research on genetics of esophageal cancer found: Patients with esophageal cancer