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目的:研究参香养胃胶囊抗SD大鼠胃溃疡及抗胃黏膜损伤的作用。方法:采用水浸应激法、幽门结扎法、利血平法、醋酸等方法致大鼠胃溃疡,盐酸-乙醇、吲哚美辛致大鼠急性胃黏膜损伤,进行抗胃溃疡和胃黏膜保护实验。结果:参香养胃胶囊能明显抑制水浸应激、幽门结扎、利血平以及醋酸致大鼠胃溃疡;并对盐酸-乙醇、消炎痛所致大鼠急性胃黏膜损伤有明显的抑制作用;结论:参香养胃胶囊具有抗溃疡的作用。
Objective: To study the effects of Shenxiang Yangwei Capsule on gastric ulcer and anti-gastric mucosal injury in SD rats. METHODS: Rat gastric ulcers, hydrochloric acid-ethanol, and indomethacin-induced acute gastric mucosal injury were induced by water immersion stress test, pyloric ligature, reserpine, and acetic acid. Rat gastric ulcers and gastric mucosa were treated. Protection experiment. RESULTS: Shenxiang Yangwei Capsule can significantly inhibit water-immersion stress, pyloric ligature, reserpine, and acetic acid-induced gastric ulcer in rats; and it has a significant inhibitory effect on acute gastric mucosal injury in rats induced by hydrochloric acid-ethanol and indomethacin. Conclusion: Shenxiang Yangwei Capsule has antiulcer effect.