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目的:分析高血压伴糖尿病应用缬沙坦联合硝苯地平治疗的临床价值。方法:随机选取2014年2月至2016年2月我院收治的60例高血压伴糖尿病患者临床资料分析,根据随机数字法,把60例患者分成对照组与观察组,各30例。对照组仅应用硝苯地平治疗,观察组应用硝苯地平联合缬沙坦治疗,比较两组治疗效果和指标改善情况。结果:观察组总有效率93.3%,对照组总有效率73.3%,观察组总有效率明显比对照组高,两组对比差异显著(P<0.05);观察组收缩压、舒张压、血肌酐、血尿素氮、微量白蛋白、糖化血红蛋白等指标改善情况明显优于对照组,两组对比差异显著(P<0.05)。结论:高血压伴糖尿病应用缬沙坦联合硝苯地平治疗能明显提高治疗效果,还能保护患者肾脏,值得推广应用。
Objective: To analyze the clinical value of valsartan combined with nifedipine in the treatment of hypertension and diabetes mellitus. Methods: The clinical data of 60 hypertensive diabetic patients treated in our hospital from February 2014 to February 2016 were randomly selected. According to the random number method, 60 patients were divided into control group and observation group, with 30 cases in each group. The control group was treated with nifedipine only. The observation group was treated with nifedipine plus valsartan. The therapeutic effects and indexes of the two groups were compared. Results: The total effective rate was 93.3% in the observation group and 73.3% in the control group. The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The systolic blood pressure, diastolic blood pressure, , Blood urea nitrogen, microalbumin, glycosylated hemoglobin and other indicators improved significantly better than the control group, significant difference between the two groups (P <0.05). Conclusion: The combination of valsartan and nifedipine in patients with hypertension and diabetes mellitus can obviously improve the therapeutic effect, and protect the kidney of patients. It is worth popularizing and applying.