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许多具有抗癌能力的抗生素,如阿霉素,链黑霉素,博来霉素等都具有醌式结构。它们可以通过半醌自由基与氧反应,生成超氧阴离子自由基(O_2~-)。这一过程可被看作一般醌类抗癌药的共同机理。维生素K_3(甲萘醌)是
Many anti-cancer antibiotics, such as doxorubicin, streptozotocin, bleomycin and so on have quinone structure. They can react with oxygen through half quinone free radicals to generate superoxide anion radical (O2 ~ -). This process can be seen as a common mechanism of quinone anti-cancer drugs in general. Vitamin K_3 (menadione) is