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目的探讨伴有严重过敏性鼻炎小儿鼾症的有效治疗方法。方法病例为2015年5月至2016年6月我院门诊收治的60例伴有严重过敏性鼻炎小儿鼾症,依据随机对照原则分为实验组(30例)与对照组(30例),所有病例使用抗生素治疗1周,同时联合使用丙酸氟替卡松鼻喷雾剂、左西替利嗪治疗1周;实验组晨起空腹加用强的松5mg,超过9岁口服10mg/d,连续用药1周后停药,饭后再加用一片儿童维生素D钙咀嚼片,对照组同期给予安慰剂。一周后两组同时联合使用丙酸氟替卡松鼻喷雾剂、左西替利嗪、孟鲁司特钠以及维生素D钙咀嚼片治疗4周;治疗前、治疗1周后、治疗4周后患者的症状评分根据Carlos O’Connor-Reina的家长调查问卷获得。结果与治疗前相比,实验组及对照组症状评分均呈明显下降趋势,差异均有统计学意义(P<0.05)。治疗后第1周,实验组各项症状评分均低于对照组,差异均有统计学意义(P<0.05);实验组总有效率100%,对照组总有效率40%,二组有效率差异有统计学意义(P<0.05)。治疗后第4周,实验组各项症状评分均低于对照组,差异均有统计学意义(P<0.05);实验组总有效率100%,对照组总有效率63.33%,二组有效率差异有统计学意义(P<0.05)。结论强的松联合维生素D钙咀嚼片在伴有严重过敏性鼻炎小儿鼾症治疗中有明显的辅助治疗作用。
Objective To investigate the effective treatment of snoring in children with severe allergic rhinitis. Methods From May 2015 to June 2016, 60 cases of pediatric snoring patients with severe allergic rhinitis treated in our hospital were divided into experimental group (30 cases) and control group (30 cases) according to randomized control principle. The patients were treated with antibiotics for 1 week, while fluticasone propionate nasal spray and levocetirizine were used for 1 week. In the morning, the rats in the experimental group were treated with prednisone 5 mg and oral 10 mg / d over 9 years old for 1 week After the withdrawal, add a child after meals with vitamin D calcium chewable tablets, the control group was given placebo at the same period. One week later, the two groups were treated with fluticasone propionate nasal spray, levocetirizine, montelukast sodium and vitamin D chewable tablets for 4 weeks. Before treatment, after 1 week of treatment, the symptoms of patients Scores were based on Carlos O’Connor-Reina’s parental questionnaire. Results Compared with before treatment, symptom scores of experimental group and control group showed a significant downward trend, the differences were statistically significant (P <0.05). The first week after treatment, the symptoms of the experimental group were lower than the control group, the difference was statistically significant (P <0.05); the total effective rate was 100% in the experimental group, the control group, the total effective rate was 40% The difference was statistically significant (P <0.05). At the 4th week after treatment, all the symptom scores in the experimental group were lower than those in the control group (P <0.05). The total effective rate was 100% in the experimental group and 63.33% in the control group. The effective rate The difference was statistically significant (P <0.05). Conclusion Prednisone combined with vitamin D calcium chewable tablets in children with severe allergic rhinitis snoring treatment has obvious adjuvant therapy.