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目的 比较 1999年WHO及 2 0 0 1年美国第三次胆固醇教育计划 (ATPⅢ )中提出的两种代谢综合征 (MS)工作定义在中国人群中应用的价值。方法 由 1999～ 2 0 0 1年上海华阳和曹杨社区肥胖及其相关疾病基线调查资料中 ,取年龄为 2 0～ 74岁人群有完整血糖、血脂、血压、胰岛素、尿微量白蛋白、尿肌酐等资料者共 2 0 4 8人 (男性 896人 ,女性 115 2人 )。分别应用WHO(1999)及ATPⅢ的MS工作定义诊断MS ,并比较MS的患病率及其构成组分患病率的异同。结果 (1)WHO(1999)及ATPⅢ定义诊断出的MS患病率分别为 17 14 %和 10 95 % ,前者显著高于后者。 (2 )两种定义诊断MS的一致率为 4 5 17% ,另有 4 2 0 2 %的MS仅符合WHO(1999)定义 ,12 81%的MS仅符合ATPⅢ定义。 (3)WHO(1999)定义诊断出的高血糖及腹型肥胖是ATPⅢ (2 0 0 1)定义的 1 74及 4 38倍(16 74 %比 9 5 7% ,33 0 4 %比 7 5 4 % )。 (4)两种定义诊断的MS者的体重指数、腰围与臀围比、血压、血糖、胰岛素抵抗指数、尿白蛋白 /肌酐比值都显著高于非MS者。结论 用两种定义诊断的MS都能较好地反映MS者代谢异常集聚的程度 ;WHO(1999)较ATPⅢ工作定义更能反映中国人群MS及构成组分的特点 ,能诊断出更多的MS。
Objective To compare the value of two definitions of metabolic syndrome (MS) work proposed by the WHO and the third ATP program in 2001 in the Chinese population. Methods From baseline survey data of obesity and related diseases in Shanghai Huayang and Cao Yang communities from 1999 to 2001, complete blood glucose, blood lipid, blood pressure, insulin, urine microalbuminuria and urine Creatinine and other information were a total of 2048 people (896 males, 115 females). MS (1999) and MS (MS) of ATP Ⅲ were used respectively to diagnose MS and to compare the prevalence of MS and the prevalence of its constituent components. Results (1) The prevalence of MS diagnosed by WHO (1999) and ATPⅢ was 17 14% and 10 95% respectively, the former was significantly higher than the latter. (2) The coincidence rates of the two definitions of diagnosing MS were 45.17%, while another 42.02% of the MS only met the definition of WHO (1999), while 12.81% of MS only met the definition of ATPIII. (3) The diagnosis of hyperglycemia and abdominal obesity as defined by the WHO (1999) is 1 74 and 4 38 times as defined by ATP III (2001) (16 74% vs. 95 7%, 340 4% vs. 75 4%). (4) The body mass index, waist circumference and hip circumference ratio, blood pressure, blood glucose, insulin resistance index, urinary albumin / creatinine ratio were significantly higher in the two defined MS patients than in non-MS patients. Conclusion The diagnosis of MS with two kinds of definitions can better reflect the degree of metabolic abnormalities in MS. WHO (1999) can better reflect the characteristics of MS and its constituent components in Chinese population than the definition of ATP Ⅲ, and more MSs can be diagnosed .