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目的探讨卡托普利导致心血管方面的不良反应及其预防措施。方法选取我院2014年3月至2015年3月间由于使用卡托普利治疗造成心血管不良反应的患者病历,数量50例。对所有患者的临床治疗进行分析。结果使用卡托普利治疗后出现的常见心血管不良反应为窦性心动过快、低血压、下壁心肌梗死、血压升高以及房室传导阻滞。20例患者在经过对症治疗后完全恢复正常,另30例患者在降低药量或是停药后血压完全正常。结论使用卡托普利进行治疗会造成心血管方面的不良反应,因此在治疗过程中需要关注患者适应证,并严格规定用法用量,一旦出现不良反应后需要立即停药并进行针对性处理。
Objective To investigate the cardiovascular adverse effects caused by captopril and its preventive measures. Methods A total of 50 cases of patients with cardiovascular adverse reactions caused by using captopril during our hospital from March 2014 to March 2015 were selected. All patients were analyzed for clinical treatment. Results Common adverse cardiovascular events after captopril treatment were sinus tachycardia, hypotension, inferior myocardial infarction, elevated blood pressure, and atrioventricular block. Twenty patients recovered completely after symptomatic treatment, and the other 30 patients had complete normal blood pressure after reducing the dosage or stopping the medicine. Conclusions Treatment with captopril causes cardiovascular adverse effects. Therefore, attention should be paid to the indications of patients during the course of treatment, and the usage and dosage should be strictly regulated. Once adverse reactions occur, immediate withdrawal and targeted treatment should be performed.