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目的 总结高危良性前列腺增生(BPH )患者行经尿道前列腺等离子大标本电切术(TUIRP)的临床效果.方法 回顾性分析38例高危大体积BPH行 TUIRP患者的临床资料 ,分析其临床效果.结果 手术均获得成功.手术时间(54.8 ± 10.3) min ,前列腺组织重(69.7 ± 10.4) g ,术中出血量(95.6 ± 12.8) ml ,5例给予输血治疗.术中无包膜穿孔、水中毒及闭孔神经反射发生.术后有5例发生出血 ,膀胱痉挛4例 ,尿路感染5例 ,暂时性尿失禁2例 ,尿道狭窄2例.与术前比较 ,术后国际前列腺症状评分下降[(11.5 ± 2.2)分 vs .(25.7 ± 3.1)分] ,尿流率加快[(13.1 ± 3.6) ml/s vs .(5.4 ± 3.9) ml/s] ,残余尿量减少[(39.5 ± 10.2) ml vs .(228.5 ± 63.5) ml] ,生活质量指数改善(2.4 ± 0.4 vs .5.2 ± 0.7)(P<0 .05).结论 高危大体积BPH患者行TUIRP安全、有效.“,”Objective To summarize the clinical outcomes of transurethral isoionic resection of the prostate(TUIRP) in the high risk patients with large volume of benign prostatic hyperplasia (BPH) .Methods The outcomes of 38 high risk patients with large volume of BPH underwent TUIRP were retrospectively analyzed .Results The TUIRP was performed successfully in all cases with operation time of (54.8 ± 10.3) minutes and blood loss of (95.6 ± 12.8) ml in average(5 cases transfused) .The prostate tissues resected weighted (69.7 ± 10.4) g .There was no case with capsular perforation ,water intoxication ,and obturator nerve reflex .The postoperative complications included slight bleeding in 5 cases ,bladder spasm in 4 cases ,urinary tract infection in 5 cases ,temporary urinary incontinence in 2 cases ,and urethral stricture in 2 cases .Compared to before ,IPSS score in three months after operation was decreased [(11.5 ± 2.2) points vs .(25.7 ± 3.1) points] ,Qmax was increased[(13.1 ± 3.6)ml/s vs .(5.4 ± 3.9) ml/s] ,residual urine decreased[(39.5 ± 10.2) ml vs . (228.5± 63.5)ml],andQOLindexwasimproved(2.4±0.4vs.5.2±0.7)(P<0.05).Conclusion TUIRP is safe and effective in the treatment of high risk patients with large volume of BPH .