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目的观察耐甲氧西林金黄色葡萄球菌(MRSA)和金黄色葡萄球菌(SA)对常用消毒剂抗性情况,为消毒剂的合理应用提供技术依据。方法采用次氯酸钠、二氧化氯、碘伏、季铵盐、醋酸氯己定对MRSA标准株(ATCC33591)和SA标准株(ATCC 6538)进行悬液定量杀菌试验,以细菌杀灭对数均值评价杀灭效果。结果该5种常见消毒剂对SA标准株的杀灭效果均低于MRSA标准株。结论人体皮肤与手部消毒及环境用消毒剂,其使用剂量可根据消毒学试验代表菌株金黄色葡萄球菌(ATCC 6538)的处理剂量进行选择,避免过度消毒导致环境污染及耐消毒剂菌株的产生。
Objective To observe the resistance of methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus (SA) to common disinfectants and to provide technical basis for the rational application of disinfectants. Methods The MRSA standard strain (ATCC33591) and the SA standard strain (ATCC 6538) were quantitatively tested for bactericidal activity using sodium hypochlorite, chlorine dioxide, iodophor, quaternary ammonium salts and chlorhexidine acetate. Off effect. Results The killing effects of the five common disinfectants on SA standard strains were lower than those of MRSA standard strains. Conclusion The human skin and hand disinfection and environmental disinfectants, the use of doses according to the disinfection test representative strain Staphylococcus aureus (ATCC 6538) treatment dose to avoid over-disinfection lead to environmental pollution and disinfectant strains .