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自从1985年Rosenberg[1]首次报道用人外周血淋巴细胞于体外经白细胞介素2（IL－2）激活扩增后回输病人体内治疗晚期恶性肿瘤获得成功以来，一种基于刺激自然免疫反应的肿瘤生物学治疗方法正在兴起。过继免疫疗法（ACI）即将免疫反应物如免疫细胞转输入荷瘤人体或动物。在过去的
Since Rosenberg [1] first reported the use of human peripheral blood lymphocytes in vitro transfusion of interleukin 2 (IL-2) to activate and treat patients with advanced malignant tumors after transfusion, a type of stimulation based on natural immune response Cancer biology is emerging. Adoptive immunotherapy (ACI) involves the transfer of an immune response, such as an immune cell, into a tumor-bearing human or animal. in the past