对于扁桃体病灶感染的研究已有相当长的历史,1939年 Gutzeit 及 Parade 对病灶感染所下的定义如下:身体某处有局限性慢性炎症,扁桃体无症状或有时出现症状,而远离此病灶的诸脏器发生反应性器质或机能障碍,引起继发疾患,包括肾、皮肤、骨关节等疾患。临床上多见的皮肤疾患如掌蹠脓疱症、骨关节疾患如胸、肋、锁骨肥厚症,慢性关节风湿症,还有IgA 肾病,扁桃体炎性低烧等。掌蹠脓疱病、胸、肋、锁骨肥厚症及 IgA 肾病三者有时合并存在,此时称为“扁桃体病灶性皮肤、关节、 There is a long history of research on tonsillectomy. In 1939 Gutzeit and Parade defined focal infections as follows: chronic inflammation somewhere in the body, asymptomatic or sometimes symptomatic tonsils, and far away from this lesion Reactive organ or organ dysfunction, causing secondary disorders, including kidney, skin, bone and joint disorders. Clinically common skin disorders such as palmoplantar pustulosis, osteoarthritis such as chest, ribs, clavicular hypertrophy, chronic rheumatoid arthritis, as well as IgA nephropathy, tonsil inflammatory fever and so on. Palmoplantar pustulosis, thoracic, costal, clavicular hypertrophy and IgA nephropathy sometimes combined with the existence of three, then called "tonsil focal skin, joints,