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目的观察1,6-二磷酸果糖联合奥扎格雷钠治疗糖尿病合并脑梗死的疗效。方法将3年来诊治的60例糖尿病合并脑梗死患者随机分为治疗组和对照组,在常规治疗的基础上,治疗组采用1,6-二磷酸果糖50 ml静脉滴注,20 min滴完,每日2次;奥扎格雷钠80 mg加入0.9%生理盐水250 ml中静脉滴注,每日2次。对照组单用1,6-二磷酸果糖50 ml静脉滴注,20 min滴完,每日2次,两组疗程均为14 d。观察临床总有效率。结果治疗组总有效率(96.67%)与对照组(80%)比较差异有统计学意义(P<0.01)。结论 1,6-二磷酸果糖与奥扎格雷钠治疗糖尿病合并脑梗死疗效显著。
Objective To observe the efficacy of fructose-1,6-diphosphate combined with ozagrel on diabetic patients with cerebral infarction. Methods Sixty patients with diabetes mellitus complicated with cerebral infarction who were diagnosed and treated in three years were randomly divided into treatment group and control group. On the basis of conventional treatment, the treatment group received intravenous drip of 50 ml fructose-1,6- 2 times a day; Ozagrel sodium 80 mg 0.9% saline 250 ml infusion, 2 times a day. Control group alone with fructose 1, 6 - diphosphate 50 ml intravenous drip finished 20 min, 2 times a day, two courses of treatment were 14 d. Observe the total clinical efficiency. Results The total effective rate (96.67%) in the treatment group was significantly different from that in the control group (80%) (P <0.01). Conclusion Fructose 1, 6-diphosphate and ozagrel sodium have significant therapeutic effect on diabetic cerebral infarction.