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目的比较非洛地平缓释片与福辛普利钠片治疗肾性高血压的临床疗效。方法选取2014年2月—2015年10月四川省人民医院收治的肾性高血压患者60例,随机分为研究组和对照组,各30例。研究组予以非洛地平缓释片治疗,对照组予以福辛普利钠片治疗。观察两组患者的临床疗效及不良反应发生情况。结果研究组总有效率为96.7%,高于对照组的83.3%,差异有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论非洛地平缓释片治疗肾性高血压的临床疗效好于福辛普利钠,且血压控制效果好,安全性高。
Objective To compare the clinical efficacy of felodipine sustained-release tablets and fosinopril sodium tablets in the treatment of renal hypertension. Methods Sixty patients with renal hypertension admitted from Sichuan Provincial People’s Hospital from February 2014 to October 2015 were randomly divided into study group and control group, with 30 cases in each group. The study group was treated with felodipine sustained-release tablets, while the control group was treated with fosinopril sodium tablets. The clinical efficacy and adverse reactions of the two groups were observed. Results The total effective rate of the study group was 96.7%, which was higher than that of the control group (83.3%), the difference was statistically significant (P <0.05). Two groups of patients with adverse reactions, the difference was not statistically significant (P> 0.05). Conclusion The clinical efficacy of felodipine extended release tablets in the treatment of renal hypertension is better than that of fosinopril sodium, and the effect of blood pressure control is good and safe.