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应用放射性核素功能测定或肾动态显像获得肾小球滤过率(GFR)是临床常用的测量方法,核素显像的特点在于获得肾血流和尿路排泄系列影像的同时计算 GFR 及其他参数,方法实用简便,GFR 数值通常与临床判断或与其他计算 GFR 的方法相吻合。但核素显像测量 GFR 受多种因素的影响,包括测量放射性剂量的准确性、“弹丸”注射技术、患者的体形变异和肾脏位置差异、肾脏疾病严重程度和肾外因素干扰、计算机处理方法和操作技能因素等,因此计算 GFR 的精确度存在不确定性,临床要特别注重参考其他相关指标综合评估肾脏的功能状态。
The application of radionuclide or renal dynamic imaging to obtain glomerular filtration rate (GFR) is a commonly used clinical measurement method, radionuclide imaging is characterized by the acquisition of renal blood flow and urinary tract excretion series of images while calculating the GFR and Other parameters, methods and practical simplicity, GFR values are generally consistent with clinical judgment or with other methods to calculate GFR. However, the determination of GFR by radionuclide imaging is influenced by a number of factors, including the accuracy of radioactive dose measurements, injection technique, differences in patient’s body shape and kidney position, severity of renal disease and extra-renal factors, Treatment methods and operational skills, so there is uncertainty in the calculation of GFR accuracy, clinical special attention should be paid to refer to other relevant indicators comprehensive assessment of renal function status.